Vacancies with Registered CTUs

Job title: CTU Data Manager
Salary: £30,378 to £34,610 per annum (pro rata)
Contract type: Fixed term until 31 December 2026
Working pattern: Part time considered up to a maximum of 0.5 FTE (18.75 hours)
Closing date: 1 September 2025 (11:59pm)
 
About the role
An exciting opportunity has arisen for a data manager to join the Brighton and Sussex Clinical Trials Unit. As Data Manager you will work within the data team on a mixed portfolio of projects. 
 
The role involves data review and discrepancy management to ensure data quality and consistency; development of Case Report Forms (CRFs), Data Management Plans (DMPs), Clinical Trial Databases and implement data validation and quality control procedures for individual trials in accordance with Good Clinical Practice (GCP) standards. Appropriate study training will be provided.
 
Brighton and Sussex Clinical Trials Unit is a UKCRC registered CTU based in the Brighton and Sussex Medical School and is involved in the design, conduct and analysis of RCTs and CTIMPs encompassing a range of disease areas (www.bsms.ac.uk/ctu)
 
About you
You will be educated to degree level or with equivalent experience, proactive with a positive and flexible attitude and exceptional communication skills. You will be well-organised, able to plan your workload effectively, and adaptable to changing priorities.
 
Further information
Please contact Gavin Peacock (CTU Information Systems Manager) g.peacock2@bsms.ac.uk for informal enquiries.
 
For a full role description, and to apply, please click here.

Job title: Lead Clinical Data Manager
Salary: £54,617 – £60,901 per annum
Contract type: Fixed term for 2 years
Working pattern: Full time
Closing date: 4 September 2025 (23:55)
 
About the Role
We are seeking an experienced senior project/data manager or database developer with leadership experience to lead our team of clinical trials data management and database development staff in supporting a growing portfolio of clinical trials in priority areas for the NHS. The post-holder will have significant input into strategic development of the team, and systems and processes.

The role-holder will provide leadership on all data management and database development activities across the lifecycle, including liaison with and advice to study teams, planning, building and supporting new and existing study databases for clinical research, using EDC systems such as OpenClinica and RedCap. It will also involve developing and documenting data management processes, as well as line management and supervision of junior colleagues.

About You
An undergraduate degree or above, with substantial relevant experience in data management or database development is required.  You will have in-depth experience of building and managing study databases with EDC tools, experience of developing and documenting data management processes and SOPs, line management experience, as well as a good understanding of the regulatory framework around data management and information governance.
 
For a full role description, and to apply, please click here.

Job title: Clinical Trial Data Manager
Salary: £38,682 to £46,580 per annum
Contract type: Permanent
Working pattern: Full time
Closing date: 7 September (midnight)
 
About us
Papworth’s Trials Unit Collaboration (PTUC) and is based in the Heart and Lung Research Institute (HLRI), near Royal Papworth Hospital on the Cambridge Biomedical Campus. The Data Management (DM) team works within PTUC to generate high quality data for our trials.
 
About the role
This role is integral to the DM team, and it is an excellent opportunity to utilise your clinical trial data management skills in all study types, including CTIMPs, devices and multi-site studies. Being involved at all trial stages, from protocol design to database lock.
 
The post holder will be responsible for designing, implementing, and maintaining database systems and resources for the recording of clinical trials data, ensuring that they are compliant with appropriate regulatory requirements.
 
They will also work closely with PTUC’s statisticians to provide support to the design, monitoring, and analysis of data sets (using R). Working as a liaison between the statisticians and the DM team, to improve data analysis.
 
About you
You will have significant data management experience, within a clinical trial setting. You will have experience of using clinical data management systems and designing electronic case report forms and data validations. Previous line management experience would be beneficial.
 
For a full role description, and to apply, please click here.

Job title: (Senior) Clinical Trials Database Developer
Salary: £40,015 – £51,755 per annum
Contract type: Fixed term for 1 year
Working pattern: Full time
Closing date: 16 September 2025 (23:55)
 
About the Role
We are seeking an enthusiastic and experienced (Senior) Clinical Trials Database Developer to join our team of data management and IT staff supporting a growing portfolio of clinical trials. This post will be offered at either Grade 4 (Database Developer) or Grade 5 (Senior Database Developer) based on experience. The post holder will take responsibilities for database development and data management activities for a number of clinical research studies supported by the Pragmatic Clinical Trials Unit (PCTU) with the senior post overseeing and leading these activities.

About You
The successful candidate will be educated to Degree level or above, with relevant experience of building trial databases using EDC systems in clinical research. Essential requirements include experience of developing relevant data management processes and documentation and good understanding of the regulatory framework around data protection and information governance.
 
For a full role description, and to apply, please click here.

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Job title: Head of Quality Assurance
Salary: £46,049 to £58,225 per annum
Contract type: Fixed Term for 5 Years
Working pattern: Full time
Closing date: 12 September 2025
 
An exciting opportunity to join the Southampton Clinical Trials Unit (SCTU), within the University of Southampton, in a senior leadership role as the Head of Quality Assurance. 

SCTU is a leading UK academic CTU located within the state-of-the-art Centre for Cancer Immunology building at Southampton General Hospital https://www.thinglink.com/mediacard/1575453151220203523. SCTU is a UKCRC registered CTU and is core-funded by Cancer Research UK (CRUK) together with funding from the National Institute for Health and Care Research (NIHR) via the Biomedical Research Centre (BRC) and Research Support Service (RSS). 

SCTU has expertise in the design, conduct and publication of clinical trials and other well-designed studies from first-in-human phase I to practice changing phase III trials to large early diagnosis observational studies with rich translational data. Managing a growing portfolio (75% cancer, 25% non-cancer) that covers the complete spectrum of clinical practice, from primary care through to tertiary referral medicine, including pan-cancer experimental therapeutics, surgery, radiotherapy and early diagnosis. Undertaking multi-centre early and late phase clinical trials, we work nationally and internationally to create the evidence for patient benefit that will directly influence routine clinical practice in the NHS and overseas. 

The Head of QA will have a senior leadership role within SCTU, providing strategic and operational oversight for QA, pharmacovigilance and monitoring. SCTU has an established portfolio to CTIMP, NIMP and device trials in the UK with a developing portfolio of international trials with its first trials open in Australia and existing collaborations with Canada, Ireland and other European countries. SCTU currently have just over 120 plus staff with the expectation of further growth over the next 5 years as research opportunities arise. 

This is a rare and exciting opportunity for someone to lead the QA for SCTU in close consultation with the SCTU Director and Associate Directors. The post holder will also work with CRUK Head Office in strategic areas of development alongside sister UK CRUK CTUs and have close liaison with the numerous academic sponsors of SCTU trials.  
 
The appointed person must have proven strategic management and managing change experience, knowledge of clinical trial methodology and regulatory requirements. Having worked within a UKCRC CTU is desirable but not essential. 

For a full role description, and to apply online, please click here.

Job title: Fleming Initiative Research Fellow/Senior Statistician
Salary: £55,144 – £65,073 per annum
Contract type: Fixed term for three years in the first instance
Working pattern: Full time
Closing date: 28 August 2025

This is a readvertisement, so previous candidates need not re-apply.
 
About the role
We are looking for an ambitious senior statistician with experience in clinical trials and an interest or experience in the design and analysis of adaptive trials. You will lead the clinical trial portfolio for a research programme in antimicrobial resistance and work to support colleagues in data-enabled trials. You will also undertake statistical methods research associated with the programme with support from senior colleagues. You will collaborate on research funding proposals with clinical colleagues and develop your own funding applications for statistical methods research.
 
You will be based at the Imperial Clinical Trials Unit, where you will join a large and supportive group of statisticians working on clinical trials to lead on this exciting new exciting partnership between Imperial College London and Imperial College Healthcare NHS Trust, the Fleming Initiative, which aims to tackle antimicrobial resistance (AMR) through a people-centred and convergence science approach.
 
The Initiative is run under the Directorship of Professor Alison Holmes. This project falls within the ‘Put the patient first’ stream and is co-led by Dr Timothy Rawson and Professor Victoria Cornelius. The project involves conducting a data-enabled trial with the ultimate aim to tackle antimicrobial resistance and preparing for the development and funding for a SMART trial. The postholder will work closely with project team members and provide statistical support across related work packages to the trial. They will oversee all aspects of the trial design, implementation, conduct, and analysis, including expert statistical advice, development of study protocols and statistical analysis plans. There will be opportunity to undertake related methodology projects in SMART trial designs.
 
Further information
This is a full time, fixed term contract for 3 years in the first instance based in the Imperial Clinical Trials Unit, White City Campus.

If you require any further details about the role, please contact Professor Victoria Cornelius (v.cornelius@imperial.ac.uk).
 
For a full role description, and to apply, please click here.

Job title: Principal Statistician
Salary: £49,970 – £63,120 per annum (pro rata)
Contract type: Fixed Term for 3 years
Working pattern: Full time (part time working (minimum 60% FTE) will be considered)
Closing date: 7 September 2025
 
Summary of Role
The Cancer Research UK funded Clinical Trials and Statistics Unit at The Institute of Cancer Research (ICR-CTSU) seek an experienced and highly motivated Principal Statistician to join their team of over 20 statisticians.
We want to hear from you if you:
~ Enjoy the challenge of designing efficient clinical trials and analysing complex datasets to answer clinical questions that will make a difference in patients’ lives
~ Seek variety in your work and opportunities to apply your statistical knowledge across multiple therapeutic areas in oncology.
~ Thrive on being part of a multi-disciplinary research team with like-minded statisticians.
~ Are looking to develop your career within a dynamic and supportive academic environment at a leading cancer clinical trials unit.

ICR-CTSU manages an exciting portfolio of national and international phase II and III cancer clinical trials and an expanding number of phase I trials. You will work as part of a multi-disciplinary team on the statistical design and development of new trials. You will conduct and oversee analysis of a number of clinical trials and/ or associated imaging or translational biomarker research studies across our portfolio.

Key Requirements
The successful applicant will be an experienced and highly motivated medical statistician interested in applying their statistical knowledge to the design and analysis of patient-centred clinical trials. They will have a post-graduate qualification in statistics.  They should demonstrate a solid understanding of clinical trials and experience in applying statistical methods to real-world data. Effective oral and written communication skills, as well as enthusiasm for collaborating with others from diverse disciplines, are essential.
Additional information

This is an office based role. Requests for hybrid working (splitting time between our Sutton site and home) may be considered following successful completion of key training and only if the role allows. Flexible working options may be considered.
For informal discussion about the role please contact Nuria Porta, email Nuria.Porta@icr.ac.uk
 
For more details and to apply, please visit our recruitment website:  Principal Statistician in Sutton – The Institute of Cancer Research

Job title: Principal Statistician (Bayesian Clinical Trials)
Salary: £55,000 to £62,000 per annum
Contract type: Permanent
Working pattern: Full time
Closing date: 21 September 2025

The Intensive Care National Audit & Research Centre (ICNARC) is an independent, not-for-profit, scientific organisation. Our work helps improve the quality of critical care through audit, research and education, conducted with, and in the interests of, patients and those who care for them.
 
About the role
This is an exciting opportunity to join a UKCRC-registered Clinical Trials Unit (CTU) that is designing and delivering cutting-edge clinical trials employing frequentist and Bayesian methods in adaptive and platform trial designs. We are looking for a Principal Statistician to provide statistical expertise in Bayesian trial design and analysis to support the delivery of our portfolio of critical care research, including the recently funded PIVOTAL platform trial in paediatric intensive care, and to lead the design of future Bayesian trials. The role will also include the opportunity for involvement in our National Audit Programme (an umbrella of four national clinical audits managed by ICNARC), which delivered high-profile analyses reporting on intensive care during the COVID-19 pandemic.
 
For a full role description, and to apply online, please click here.

Job title: Biostatistician
Salary: £36,636 to £46,049 per annum (pro rata)
Contract type: Fixed term up to January 2028
Working pattern: Full time
Closing date: 22 September 2025

Background
This is an exciting opportunity to join one of the largest UK Clinical Research Collaboration (UKCRC) registered clinical trials units in the country. The Cancer Research UK Clinical Trials Unit (CRCTU) is a Department within the School of Medical Sciences at the University of Birmingham. The CRCTU employs a multidisciplinary team of around 200 staff including statisticians, trial management staff, research nurses, monitors, programmers, administrators and IT staff. It specialises in running early and late phase clinical trials in adults and children. Alongside trials portfolios in a broad range of adult solid cancers and haemato-oncology, CRCTU is the national lead for prestigious programmes of children’s cancer and leukaemia trials. The unit also includes two trials teams dedicated to non-cancer trials: the Diagnostics, Drugs, Devices and Biomarkers team (D3B), running mainly early-phase trials, and the Inflammation, Advanced and Cellular Therapy (I-ACT)team, specialising in trials in rheumatology and advanced therapies. 
 
The post holder will work within the CRCTU Biostatistics Group, which currently include 28 biostatisticians, who are working on trials and methodological projects, mainly in adult and paediatric oncology. This post provides an excellent opportunity for a biostatistician to apply their experience and expertise within a leading academic trials unit undertaking methodologically challenging research.
 
Role Summary
This post is for a Biostatistician to be the main statistical scientist for a methodological project on improving statistical methods for the design and analysis of clinical trials in paediatric cancer, funded by the UKRI Better Methods, Better Research Programme. This project will focus on the use of ordinal longitudinal outcomes and appropriate statistical modelling, investigating whether use of these methods will improve statistical efficiency, and exploring specification of outcomes and presentation of the results. 
 
The post holder will co-ordinate the project, in collaboration with the investigators, ensuring that its aims are achieved on time and on budget. The project will involve liaison with the project investigators (in Birmingham and other institutions), as well as clinicians and patient representatives. The post holder will also take the lead in presentation and publication of the project’s outputs.

The Biostatistician will have opportunities to collaborate with other members of the Cancer Research UK Clinical Trials Unit (CRCTU) Biostatistics Group on various projects, and to contribute to teaching at undergraduate and postgraduate level. 
 
Informal enquiries can be made to Professor Simon Gates, email: S.Gates@bham.ac.uk.
 
For a full role description, and to apply online, please click here.

Job title: Medical Statistician
Salary: £34,982-£38,674 per annum
Contract type: Fixed term for two years
Working pattern: Full time
Closing date: 26 September 2025 (12 noon)
 
An exciting opportunity has arisen for a Medical Statistician to join the Oxford Clinical Trials Research Unit (OCTRU) Statistics Team and the Centre for Statistics in Medicine (CSM). The post is based within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), and located at the Botnar Research Centre, Oxford.
 
 About the role
You will contribute to the design, conduct, analysis and presentation of results of collaborative clinical research projects, mostly randomised clinical trials as part of the OCTRU statistics team. As a Medical Statistician working in the team, you will assist in the design and set up of clinical research projects within a multidisciplinary team, prepare statistical analysis plans (SAP) and provide written statistical input into protocols and ethics committee submissions. You will attend and occasionally contribute to OCTRU/CSM activities such as seminars, conferences, workshops and other events. 
 
 About you
You will have a postgraduate degree in statistics (or closely related subject), a substantial part of which relates to medical statistics, or equivalent experience. You will be fluent with key aspects of study design and analysis and aware of the latest statistical techniques. You will have good project management skills including the ability to manage and prioritise short- and long-term projects. Proficient knowledge of statistical software (i.e. Stata, SAS or R) as well as good verbal and written communications skills are essential. Proficiency in statistical programming and experience of producing statistical reports and contributing to peer-review publications are desirable.
 
Further information
For informal queries please contact Jonathan Cook jonathan.cook@ndorms.ox.ac.uk or octru-stats@ndorms.ox.ac.uk
 
For a full role description, and to apply, please click here.

Job title: Trial Manager
Salary: £38,674 – £46,913 per annum (pro rata)
Contract type: Fixed term until 31 October 2026
Working pattern: Full time (part time up to 80% FTE considered)
Closing date: 5 September 2025 (noon)

The National Perinatal Epidemiology Unit, Clinical Trials Unit (NPEU CTU) are looking for an enthusiastic Trial Manager to join our team to provide project management for randomised controlled trials on the NPEU CTU portfolio. This is a great opportunity to join a friendly, supportive team with scope to contribute to wider development work of the Clinical Trials Unit.
 
The postholder will be based within the Nuffield Department of Population Health (NDPH) which contains world-renowned population health research groups and provides an excellent environment for multi-disciplinary research and teaching.
 
The NPEU is an internationally recognised, multi-disciplinary research unit based within the NDPH at the University of Oxford, Old Road Campus in Headington, Oxford. The unit undertakes research about pregnancy, childbirth and new-born babies.
 
 
As Trial Manager you will be the central administrative contact at the Coordinating Centre maintaining effective and efficient systems to ensure the trials are delivered according to milestones. You will co-ordinate the design, implementation and running of the clinical trials across participating hospital sites in the UK, ensuring timely data collection and Good Clinical Practice (GCP) compliance, and ensure they comply with NPEU CTU Standard Operating Procedures.
 
To be considered for this role you will have a degree in a biomedical or associated subject, or other relevant qualification or proven experience in clinical research. You will have line management experience, as well as an understanding of clinical research methodology, good clinical practice and knowledge of all UK regulations for clinical trials, GDPR and the research governance framework. Proven administrative, data and project management skills and excellent organisational skills and the ability to prioritise your workload are also essential for this position.
 
For informal queries about the position, please contact Kayleigh Stanbury kayleigh.stanbury@npeu.ox.ac.uk.

For a full role description, and to apply online, please click here.

Job title: Clinical Trials Monitor
Salary: £46,614 – £52,245 per annum
Contract type: Fixed term for 2 years in the first instance
Working pattern: Full time
Closing date: 18 September 2025 (~Midnight)
 
We are looking for a Clinical Trials Monitor to join the UKCRC registered Imperial Clinical Trials Unit (ICTU) team, to be responsible for clinical trial monitoring activities of the investigator sites for the WARRIORS Trial.
 
The WARRIORS Trial is an international, randomised controlled trial investigating whether early endovascular aneurysm repair (EVAR) reduces the risk of aneurysm-related mortality and rupture in women with small abdominal aortic aneurysms (AAA) compared to current standard of care. The trial aims to enrol 1,112 participants across approximately 100 sites globally, spanning 12–18 countries. In the UK specifically, 15–18 centres will recruit a total of 150 participants. A 250-participant Vanguard phase will first assess the feasibility of recruitment and the safety of early EVAR before the full trial rollout. The primary composite outcome—aneurysm-related mortality and rupture—will be assessed five years after randomisation.
 
This varied role includes monitoring, feasibility, initiation, enrolment, follow-up, and close-out of investigator sites as well as archiving, with guidance from the Clinical Trial Managers and Operations Managers. You will oversee the progress and performance of the investigator sites, including efficient recruitment and reliable data collection, and ensure project objectives and timelines are met. You will ensure that the clinical trial is being conducted in accordance with contractual agreements, trial protocol, trial-specific processes and systems, SOPs, regulatory and ethical requirements and ICH-GCP guidelines.
 
In addition to traditional monitoring responsibilities, the post-holder will contribute to embedded qualitative research activities within the trial. You will receive training in relevant qualitative methods and support the collection and documentation of qualitative data during site interactions. These insights will play an important role in improving recruitment strategies, site communication, and trial delivery across all participating centres.
 
This role requires visits to national and international investigator sites, and as such will involve travel with occasional overnight stays.
 
This post is full-time and fixed term for 2 years in the first instance. The exact work pattern can be flexible and will be discussed at the interview. You will be based at Stadium House, White City campus, close to Wood Lane and White City tube stations.
 
For a full role description, and to apply, please click here.

Job title: Communications Officer
Salary: £46,614 – £56,345 per annum (pro rata)
Contact type: Fixed term until 30 November 2027 in the first instance, with the intention to extend
Working pattern: Part time (0.8FTE/ 28 hours per week)
Closing date: 1 September 2025
 
About the role
We are looking for a highly creative, motivated, and organised person to take on the role of Communications Officer for the NIHR RSS and ICTU teams.

As a core member of the RSS Operations team, you will contribute to the delivery and development of the NIHR RSS, as well as leading on communications activities for the Imperial Clinical Trials Unit.

What you would be doing
Your NIHR RSS responsibilities (0.6FTE of the role) will be focussed on demonstrating the impact of our research support. This will include generating engaging content in a variety of formats, e.g. case studies or client-facing resources to be shared across national RSS platforms. You will ensure that all material and activities shared are accurate, accessible and on brand. You will support outreach events, including identifying opportunities with the right audiences, and supporting the delivery of these events (such as identifying venues, managing registrations and organising content).

You will also be a part of the ICTU team (0.2FTE of the role), leading on communications activities for the Unit and working closely with the Senior Management team.
 
Further information
If you require any further details about the role, please contact: Gareth O’Brien – gareth.obrien@imperial.ac.uk, RSS Operational Director
 
For a full role description, and to apply, please click here.

Job title: Research Associate in Trials Methodology
Salary: Grade 6 or 7 £33,951 – £46,049 pa (depending on experience)
Contract type: Fixed term for 24 months
Working pattern: Full time
Closing date: 25 September 2025 (23:30)
 
Are you interested in how we plan and run clinical trials? And identifying and promoting responsible research practices to reduce their environmental impact? Then read on.
 
About the role
Working together with teams from the Institute of Cancer Research, University of Aberdeen and the South African Medical Research Council, we have been awarded funding from the Wellcome Trust to reduce the environmental impact whilst ensuring the success of clinical trials. The Liverpool team will identify research gaps surrounding carbon footprinting and appraise evidence-based mitigation strategies to reduce known hotspots. Areas of interest that may be investigated include but are not limited to: outcome assessment (including core outcome sets), use of digital technology, digital exclusion, use of healthcare systems data, decentralised trials. The postholder will join the TMRP Greener Trials Group, http://methodologyhubs.mrc.ac.uk/about/working-groups/trial-conductwg/tcwg-subgroup-greener-trials/, collaborating with international groups to achieve this common goal.
 
About you
You should have: a first degree or equivalent qualification in a relevant discipline and a postgraduate degree in a relevant area; relevant experience in conducting qualitative or quantitative research including data collection and data analysis; work experience in some aspect of clinical trials, be it design, conduct or analysis.
 
For a full role description, and to apply, please click here.

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